Only if you’re sedated. I stayed wide awake through mine, which I understand is rare in the U.S. but not so uncommon in the Rest Of The World. (It was sufficiently rare that they had trouble locating the correct paperwork for the various releases). It caused mild discomfort at times, very minor pain (more of a poking) when it had to make a couple of 90 degree turns, but less trauma than a routine dental cleaning.
In exchange, I was rewarded with a widescreen display of parts of me that I’ve never seen (including a vaguely visible purple blob that was my liver and the off-ramp leading to my appendix). In close-up, the tiny claws that took tissue samples looked like a scene from Matrix. Fascinating.
A small drawback was that I was ready to leave immediately following the procedure, instead of lying around the recovery room for half an hour. Turns out, the staff relied on that time to complete the reports and paperwork. At least I could drive myself home when they were done.