There has been mention of an oxygen bottle 1/4 mile from the impact site. Medical flights typically have multiple small bottles and one large bottle mounted in the patient bed. Any miss handling of an oxygen bottle by medical crew or a mechanical failure of a bottle could have caused this.
A fire or major electrical failure is a possibility. There was no response from the Lear when PNE Tower called for a switch to departure. No further communication from the Lear.
The Mexican company had a pervious fatal accident in late 2023.